| dc.contributor |
Entomology |
|
| dc.contributor |
Fralin Life Sciences Institute |
|
| dc.creator |
Artemov, Gleb N. |
|
| dc.creator |
Stegniy, Vladimir N. |
|
| dc.creator |
Sharakhova, Maria V. |
|
| dc.creator |
Sharakhov, Igor V. |
|
| dc.date |
2018-09-21T16:41:06Z |
|
| dc.date |
2018-09-21T16:41:06Z |
|
| dc.date |
2018-09-17 |
|
| dc.date |
2018-09-21T07:12:18Z |
|
| dc.date.accessioned |
2023-03-01T18:52:43Z |
|
| dc.date.available |
2023-03-01T18:52:43Z |
|
| dc.identifier |
Artemov, G.N.; Stegniy, V.N.; Sharakhova, M.V.; Sharakhov, I.V. The Development of Cytogenetic Maps for Malaria Mosquitoes. Insects 2018, 9, 121. |
|
| dc.identifier |
http://hdl.handle.net/10919/85070 |
|
| dc.identifier |
https://doi.org/10.3390/insects9030121 |
|
| dc.identifier.uri |
http://localhost:8080/xmlui/handle/CUHPOERS/281649 |
|
| dc.description |
Anopheline mosquitoes are important vectors of human malaria. Next-generation sequencing opens new opportunities for studies of mosquito genomes to uncover the genetic basis of a <i>Plasmodium</i> transmission. Physical mapping of genome sequences to polytene chromosomes significantly improves reference assemblies. High-resolution cytogenetic maps are essential for anchoring genome sequences to chromosomes as well as for studying breakpoints of chromosome rearrangements and chromatin protein localization. Here we describe a detailed pipeline for the development of high-resolution cytogenetic maps using polytene chromosomes of malaria mosquitoes. We apply this workflow to the refinement of the cytogenetic map developed for <i>Anopheles beklemishevi.</i> |
|
| dc.description |
Published version |
|
| dc.format |
application/pdf |
|
| dc.format |
application/pdf |
|
| dc.language |
en |
|
| dc.publisher |
MDPI |
|
| dc.rights |
Creative Commons Attribution 4.0 International |
|
| dc.rights |
http://creativecommons.org/licenses/by/4.0/ |
|
| dc.subject |
cytogenetic map |
|
| dc.subject |
chromosome map |
|
| dc.subject |
malaria mosquitoes |
|
| dc.subject |
Anopheles |
|
| dc.subject |
polytene chromosomes |
|
| dc.subject |
Anopheles beklemishevi |
|
| dc.subject |
chromosome map development |
|
| dc.subject |
photomap |
|
| dc.subject |
high-pressure technique |
|
| dc.subject |
chromosome straightening |
|
| dc.title |
The Development of Cytogenetic Maps for Malaria Mosquitoes |
|
| dc.title |
Insects |
|
| dc.type |
Article - Refereed |
|
| dc.type |
Text |
|