| dc.contributor |
Massachusetts Institute of Technology. Department of Biological Engineering |
|
| dc.contributor |
Massachusetts Institute of Technology. Department of Mechanical Engineering |
|
| dc.contributor |
Zervantonakis, Ioannis K. |
|
| dc.contributor |
Kothapalli, Chandrasekhar R. |
|
| dc.contributor |
Kamm, Roger Dale |
|
| dc.creator |
Zervantonakis, Ioannis K. |
|
| dc.creator |
Kothapalli, Chandrasekhar R. |
|
| dc.creator |
Chung, Seok |
|
| dc.creator |
Sudo, Ryo |
|
| dc.creator |
Kamm, Roger Dale |
|
| dc.date |
2014-09-09T16:07:14Z |
|
| dc.date |
2014-09-09T16:07:14Z |
|
| dc.date |
2011-03 |
|
| dc.date |
2010-09 |
|
| dc.date.accessioned |
2023-03-01T18:09:52Z |
|
| dc.date.available |
2023-03-01T18:09:52Z |
|
| dc.identifier |
19321058 |
|
| dc.identifier |
http://hdl.handle.net/1721.1/89232 |
|
| dc.identifier |
Zervantonakis, Ioannis K., Chandrasekhar R. Kothapalli, Seok Chung, Ryo Sudo, and Roger D. Kamm. “Microfluidic Devices for Studying Heterotypic Cell-Cell Interactions and Tissue Specimen Cultures Under Controlled Microenvironments.” Biomicrofluidics 5, no. 1 (2011): 013406. © 2011 American Institute of Physics |
|
| dc.identifier |
https://orcid.org/0000-0002-7232-304X |
|
| dc.identifier.uri |
http://localhost:8080/xmlui/handle/CUHPOERS/278993 |
|
| dc.description |
Microfluidic devices allow for precise control of the cellular and noncellular microenvironment at physiologically relevant length- and time-scales. These devices have been shown to mimic the complex in vivo microenvironment better than conventional in vitroassays, and allow real-time monitoring of homotypic or heterotypic cellularinteractions.Microfluidic culture platforms enable new assay designs for culturing multiple different cell populations and/or tissue specimens under controlled user-defined conditions. Applications include fundamental studies of cell population behaviors, high-throughput drug screening, and tissue engineering. In this review, we summarize recent developments in this field along with studies of heterotypic cell-cell interactions and tissue specimen culture in microfluidic devices from our own laboratory. |
|
| dc.description |
National Science Foundation (U.S.) (Grant EFRI-0735997) |
|
| dc.description |
IR&D Project DL-H-550151 |
|
| dc.description |
Charles Stark Draper Laboratory |
|
| dc.description |
Singapore-MIT Alliance for Research and Technology |
|
| dc.description |
National Institute for Biomedical Imaging and Bioengineering (U.S.) (Grant EB003805) |
|
| dc.format |
application/pdf |
|
| dc.language |
en_US |
|
| dc.publisher |
American Institute of Physics (AIP) |
|
| dc.relation |
http://dx.doi.org/10.1063/1.3553237 |
|
| dc.relation |
Biomicrofluidics |
|
| dc.rights |
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. |
|
| dc.source |
PMC |
|
| dc.title |
Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments |
|
| dc.type |
Article |
|
| dc.type |
http://purl.org/eprint/type/JournalArticle |
|