| dc.contributor |
Massachusetts Institute of Technology. Department of Chemistry |
|
| dc.contributor |
McGowan, Meredeth A. |
|
| dc.contributor |
Henderson, Jaclyn L. |
|
| dc.contributor |
Buchwald, Stephen Leffler |
|
| dc.creator |
McGowan, Meredeth A. |
|
| dc.creator |
Henderson, Jaclyn L. |
|
| dc.creator |
Buchwald, Stephen Leffler |
|
| dc.date |
2013-11-01T16:29:41Z |
|
| dc.date |
2013-11-01T16:29:41Z |
|
| dc.date |
2012-03 |
|
| dc.date |
2012-01 |
|
| dc.date.accessioned |
2023-03-01T18:09:39Z |
|
| dc.date.available |
2023-03-01T18:09:39Z |
|
| dc.identifier |
1523-7060 |
|
| dc.identifier |
1523-7052 |
|
| dc.identifier |
http://hdl.handle.net/1721.1/81945 |
|
| dc.identifier |
McGowan, Meredeth A., Jaclyn L. Henderson, and Stephen L. Buchwald. “Palladium-Catalyzed N-Arylation of 2-Aminothiazoles.” Organic Letters 14, no. 6 (March 16, 2012): 1432-1435. |
|
| dc.identifier |
https://orcid.org/0000-0003-3875-4775 |
|
| dc.identifier.uri |
http://localhost:8080/xmlui/handle/CUHPOERS/278978 |
|
| dc.description |
A method for the Pd-catalyzed coupling of 2-aminothiazole derivatives with aryl bromides and triflates is described. Significantly, for this class of nucleophiles, the coupling exhibits a broad substrate scope and proceeds with a reasonable catalyst loading. Furthermore, an interesting effect of acetic acid as an additive is uncovered that facilitates catalyst activation. |
|
| dc.description |
National Institutes of Health (U.S.) (Grant GM 58160) |
|
| dc.description |
National Institutes of Health (U.S.) (Postdoctoral Fellowship F32GM097771) |
|
| dc.description |
National Science Foundation (U.S.) (CHE-9808061) |
|
| dc.format |
application/pdf |
|
| dc.language |
en_US |
|
| dc.publisher |
American Chemical Society (ACS) |
|
| dc.relation |
http://dx.doi.org/10.1021/ol300178j |
|
| dc.relation |
Organic Letters |
|
| dc.rights |
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. |
|
| dc.source |
PMC |
|
| dc.title |
Palladium-Catalyzed N-Arylation of 2-Aminothiazoles |
|
| dc.type |
Article |
|
| dc.type |
http://purl.org/eprint/type/JournalArticle |
|