Sangam: A Confluence of Knowledge Streams

In Silico Investigation of Intracranial Blast Mitigation with Relevance to Military Traumatic Brain Injury

Show simple item record

dc.contributor Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
dc.contributor Massachusetts Institute of Technology. Department of Aeronautics and Astronautics
dc.contributor Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
dc.contributor Massachusetts Institute of Technology. Department of Physics
dc.contributor Radovitzky, Raul
dc.contributor Nyein, Michelle K.
dc.contributor Jason, Amanda M.
dc.contributor Yu, Li
dc.contributor Pita, Claudio M.
dc.contributor Joannopoulos, John D.
dc.contributor Radovitzky, Raul
dc.creator Nyein, Michelle K.
dc.creator Jason, Amanda M.
dc.creator Yu, Li
dc.creator Pita, Claudio M.
dc.creator Moore, David Francis
dc.creator Joannopoulos, John
dc.creator Radovitzky, Raul A
dc.date 2011-07-14T16:39:47Z
dc.date 2011-07-14T16:39:47Z
dc.date 2010-11
dc.date 2010-09
dc.date.accessioned 2023-03-01T18:06:49Z
dc.date.available 2023-03-01T18:06:49Z
dc.identifier 0027-8424
dc.identifier 1091-6490
dc.identifier http://hdl.handle.net/1721.1/64808
dc.identifier Nuein, Michelle K. et al. "In silico investigation of intracranial blast mitigation with relevance to military traumatic brain injury" PNAS 2010 107: 20703-20708.
dc.identifier https://orcid.org/0000-0002-7244-3682
dc.identifier https://orcid.org/0000-0001-6339-2708
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/278797
dc.description Blast-induced traumatic brain injury is the most prevalent military injury in Iraq and Afghanistan, yet little is known about the mechanical effects of blasts on the human head, and still less is known about how personal protective equipment affects the brain’s response to blasts. In this study we investigated the effect of the Advanced Combat Helmet (ACH) and a conceptual face shield on the propagation of stress waves within the brain tissue following blast events. We used a sophisticated computational framework for simulating coupled fluid–solid dynamic interactions and a three-dimensional biofidelic finite element model of the human head and intracranial contents combined with a detailed model of the ACH and a conceptual face shield. Simulations were conducted in which the unhelmeted head, head with helmet, and head with helmet and face shield were exposed to a frontal blast wave with incident overpressure of 10 atm. Direct transmission of stress waves into the intracranial cavity was observed in the unprotected head and head with helmet simulations. Compared to the unhelmeted head, the head with helmet experienced slight mitigation of intracranial stresses. This suggests that the existing ACH does not significantly contribute to mitigating blast effects, but does not worsen them either. By contrast, the helmet and face shield combination impeded direct transmission of stress waves to the face, resulting in a delay in the transmission of stresses to the intracranial cavity and lower intracranial stresses. This suggests a possible strategy for mitigating blast waves often associated with military concussion.
dc.description Joint Improvised Explosive Device Defeat Organization (U.S.)
dc.description United States. Army Research Office
dc.description Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
dc.format application/pdf
dc.language en_US
dc.publisher National Academy of Sciences
dc.relation http://dx.doi.org/10.1073/pnas.1014786107
dc.relation Proceedings of the National Academy of Sciences of the United States of America
dc.rights Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.source PNAS
dc.title In Silico Investigation of Intracranial Blast Mitigation with Relevance to Military Traumatic Brain Injury
dc.type Article
dc.type http://purl.org/eprint/type/JournalArticle


Files in this item

Files Size Format View
Nyein-2010-In s ... traumatic brain injury.pdf 1.728Mb application/pdf View/Open

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse