Sangam: A Confluence of Knowledge Streams

Efficient Laplace Approximation for Bayesian Registration Uncertainty Quantification

Show simple item record

dc.creator Wang, Jian
dc.creator Wells, William M.
dc.creator Golland, Polina
dc.creator Zhang, Miaomiao
dc.date 2021-11-09T19:48:22Z
dc.date 2021-11-09T19:48:22Z
dc.date 2018
dc.date 2019-09-16T16:42:32Z
dc.date.accessioned 2023-03-01T18:04:52Z
dc.date.available 2023-03-01T18:04:52Z
dc.identifier 0302-9743
dc.identifier 1611-3349
dc.identifier https://hdl.handle.net/1721.1/138063
dc.identifier Wang, Jian, Wells, William M., Golland, Polina and Zhang, Miaomiao. 2018. "Efficient Laplace Approximation for Bayesian Registration Uncertainty Quantification."
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/278671
dc.description © Springer Nature Switzerland AG 2018. This paper presents a novel approach to modeling the posterior distribution in image registration that is computationally efficient for large deformation diffeomorphic metric mapping (LDDMM). We develop a Laplace approximation of Bayesian registration models entirely in a bandlimited space that fully describes the properties of diffeomorphic transformations. In contrast to current methods, we compute the inverse Hessian at the mode of the posterior distribution of diffeomorphisms directly in the low dimensional frequency domain. This dramatically reduces the computational complexity of approximating posterior marginals in the high dimensional imaging space. Experimental results show that our method is significantly faster than the state-of-the-art diffeomorphic image registration uncertainty quantification algorithms, while producing comparable results. The efficiency of our method strengthens the feasibility in prospective clinical applications, e.g., real-time image-guided navigation for brain surgery.
dc.format application/pdf
dc.language en
dc.publisher Springer International Publishing
dc.relation 10.1007/978-3-030-00928-1_99
dc.rights Creative Commons Attribution-Noncommercial-Share Alike
dc.rights http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.source PMC
dc.title Efficient Laplace Approximation for Bayesian Registration Uncertainty Quantification
dc.type Article
dc.type http://purl.org/eprint/type/JournalArticle


Files in this item

Files Size Format View
nihms-1026606.pdf 836.5Kb application/pdf View/Open

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse