Sangam: A Confluence of Knowledge Streams

High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion

Show simple item record

dc.contributor European Commission
dc.contributor The Royal Society
dc.contributor University of Edinburgh
dc.contributor Wellcome Trust
dc.contributor Rochefort, Nathalie
dc.creator Rochefort, Nathalie
dc.creator Padamsey, Zahid
dc.creator Francioni, Valerio
dc.date 2021-04-09T09:13:55Z
dc.date 2021-04-09T09:13:55Z
dc.date.accessioned 2023-02-17T20:52:19Z
dc.date.available 2023-02-17T20:52:19Z
dc.identifier Rochefort, Nathalie; Padamsey, Zahid; Francioni, Valerio. (2021). High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion, [dataset]. University of Edinburgh. https://doi.org/10.7488/ds/3013.
dc.identifier https://hdl.handle.net/10283/3873
dc.identifier https://doi.org/10.7488/ds/3013
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/243992
dc.description Ex vivo calibration of GCaMP6s and GCaMP6f signals in soma and apical tuft dendrites of layer 5 pyramidal neurons from the mouse primary visual cortex (V1). We examined the relationship between neuronal spiking and calcium event amplitudes in proximal and distal neuronal compartments, ex vivo, by combining calcium imaging and whole-cell recordings in acute cortical slices from mouse V1. We imaged the soma and distal apical dendrite (nexus) of GCaMP6s- and GCaMP6f- expressing layer 5 neurons whilst driving neuronal spiking either by somatic current injections (somatic stimulation) or L1 electrical stimulation (dendritic stimulation). Dataset corresponding to Figure 4 and Figure 4 supplementary 1.
dc.format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
dc.format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
dc.format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
dc.format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
dc.language eng
dc.publisher University of Edinburgh
dc.relation https://github.com/rochefort-lab/Francioni-et-al.-eLife-2019
dc.relation https://elifesciences.org/articles/49145
dc.rights Creative Commons Attribution 4.0 International Public License
dc.subject calcium imaging
dc.subject whole-cell recordings
dc.subject electrophysiological recordings
dc.subject visual cortex
dc.subject mouse visual cortex
dc.subject cortical neurons
dc.subject pyramidal neurons
dc.subject dendrites
dc.subject apical tuft
dc.subject GCaMP6
dc.subject Subjects allied to Medicine::Neuroscience
dc.title High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion
dc.title Ex vivo calibration of GCaMP6s and GCaMP6f signals in soma and apical tuft dendrites
dc.type dataset
dc.coverage UK
dc.coverage UNITED KINGDOM


Files in this item

Files Size Format View
Fig 4 - GCaMP6f data.xlsx 23.21Kb application/vnd.openxmlformats-officedocument.spreadsheetml.sheet View/Open
Fig 4 - GCaMP6s data.xlsx 23.84Kb application/vnd.openxmlformats-officedocument.spreadsheetml.sheet View/Open
Fig 4 S1 - GCaMP6f data.xlsx 27.31Kb application/vnd.openxmlformats-officedocument.spreadsheetml.sheet View/Open
Fig 4 S1 - GCaMP6s data.xlsx 32.15Kb application/vnd.openxmlformats-officedocument.spreadsheetml.sheet View/Open

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse