Sangam: A Confluence of Knowledge Streams

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging

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dc.contributor MRC - Medical Research Council
dc.contributor Timmers, Paul R. H. J.
dc.creator Timmers, PRHJ
dc.creator Tiys, ES
dc.creator Sakaue, S
dc.creator Akiyama, M
dc.creator Kiiskinen, TTJ
dc.creator Zhou, W
dc.creator Hwang, S
dc.creator Yao, C
dc.creator Biobank Japan Project, The
dc.creator FinnGen Study, The
dc.creator Deelen, J
dc.creator Levy, D
dc.creator Ganna, A
dc.creator Okada, Y
dc.creator Joshi, PK
dc.creator Wilson, JF
dc.creator Tsepilov, YA
dc.date 2021-01-14T12:18:00Z
dc.date 2022-01-21
dc.date.accessioned 2023-02-17T20:52:00Z
dc.date.available 2023-02-17T20:52:00Z
dc.identifier Timmers, PRHJ; Tiys, ES; Sakaue, S; Akiyama, M; Kiiskinen, TTJ; Zhou, W; Hwang, S; Yao, C; Biobank Japan Project; FinnGen; Deelen, J; Levy, D; Ganna, A; Okada, Y; Joshi, PK; Wilson, JF; Tsepilov, YA. (2021). Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging, [dataset]. University of Edinburgh. https://doi.org/10.7488/ds/2972.
dc.identifier https://hdl.handle.net/10283/3817
dc.identifier https://doi.org/10.7488/ds/2972
dc.identifier.uri http://localhost:8080/xmlui/handle/CUHPOERS/243951
dc.description Genome-wide association summary statistics supporting the article Timmers et. al (2022) Nature Aging https://doi.org/10.1038/s43587-021-00159-8.
dc.format text/plain
dc.format application/gzip
dc.format application/gzip
dc.format application/gzip
dc.format application/gzip
dc.language eng
dc.publisher University of Edinburgh
dc.relation https://doi.org/10.1038/s43587-021-00159-8
dc.relation "Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing" Paul R. H. J. Timmers, Evgeny S. Tiys, Saori Sakaue, Masato Akiyama, Tuomo T. J. Kiiskinen, Wei Zhou, Shih-Jen Hwang, Chen Yao, The Biobank Japan Project, FinnGen Study, Joris Deelen, Daniel Levy, Andrea Ganna, Yoichiro Kamatani, Yukinori Okada, Peter K. Joshi, James F. Wilson, Yakov A. Tsepilov bioRxiv 2021.01.22.427837; doi: https://doi.org/10.1101/2021.01.22.427837 This article is a preprint and has not been certified by peer review.
dc.rights Creative Commons Attribution 4.0 International Public License
dc.subject GWAS
dc.subject GIP
dc.subject ageing
dc.subject frailty
dc.subject healthspan
dc.subject lifespan
dc.subject Mendelian randomisation
dc.subject Biological Sciences
dc.title Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging
dc.title Mendelian randomisation of genetically independent ageing phenotypes identifies LPA and VCAM1 as drug targets for human ageing
dc.type dataset
dc.coverage UK
dc.coverage UNITED KINGDOM


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