| dc.contributor |
MRC - Medical Research Council |
|
| dc.contributor |
Vitart, Veronique |
|
| dc.creator |
Iglesias, Adriana I. |
|
| dc.creator |
Mishra, Aniket |
|
| dc.creator |
Vitart, Veronique |
|
| dc.creator |
van Duijn, Cornelia M. |
|
| dc.creator |
MacGregor, Stuart |
|
| dc.creator |
on behalf of the "International Glaucoma Genetics Consortium" |
|
| dc.date |
2017-12-20T12:52:12Z |
|
| dc.date |
2018-05-01T04:15:10Z |
|
| dc.date.accessioned |
2023-02-17T20:51:53Z |
|
| dc.date.available |
2023-02-17T20:51:53Z |
|
| dc.identifier |
Iglesias, Adriana I.; Mishra, Aniket; Vitart, Veronique; van Duijn, Cornelia M.; MacGregor, Stuart; on behalf of the "International Glaucoma Genetics Consortium". (2018). Central cornea thickness Genome Wide Association Meta Analyses - Summary statistics, [dataset]. University of Edinburgh. Medical Research Council Human Genetics Unit. Institute of Genetics and Molecular Medicine. (please see attached file for full list of data publishers). https://doi.org/10.7488/ds/2270. |
|
| dc.identifier |
https://hdl.handle.net/10283/2976 |
|
| dc.identifier |
https://doi.org/10.7488/ds/2270 |
|
| dc.identifier.uri |
http://localhost:8080/xmlui/handle/CUHPOERS/243937 |
|
| dc.description |
Results from the meta-analyses of genome-wide association studies for central cornea thickness in human. Corneal thinning is a common feature of rare Mendelian connective tissue disorders, such as Ehlers-Danlos syndrome (EDS), Marfan syndrome and osteogenesis imperfecta (OI), and extreme thinning is a clinical characteristic of brittle cornea syndrome . Thinner CCT is also observed in more common ocular disorders such as keratoconus, the leading cause of corneal transplants worldwide. Dataset pertaining to the publication “Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases” which uses genetic variants imputed to the 1000 Genomes phase 1 reference in cohorts of European ancestry (14 cohorts,N=17,803) and Asian ancestry (5 cohorts, N=8,107) . |
|
| dc.format |
application/gzip |
|
| dc.format |
application/gzip |
|
| dc.format |
text/plain |
|
| dc.format |
text/plain |
|
| dc.language |
eng |
|
| dc.publisher |
University of Edinburgh. Medical Research Council Human Genetics Unit. Institute of Genetics and Molecular Medicine. (please see attached file for full list of data publishers) |
|
| dc.rights |
Creative Commons Attribution 4.0 International Public License |
|
| dc.subject |
Biological Sciences::Molecular Genetics |
|
| dc.title |
Central cornea thickness Genome Wide Association Meta Analyses - Summary statistics |
|
| dc.type |
dataset |
|